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Lower Radiotherapy Dose Shows Promise for Treating HPV-Related Oropharyngeal Cancer – Cancer Network

Given the current study findings, investigators suggested intratherapy personalization of chemoradiotherapy may possibly facilitate marked de-escalation of radiotherapy…



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De-escalation of radiotherapy to 30 Gy on the basis of intratreatment hypoxia imaging among patients with head and neck cancers related to human papillomavirus (HPV) infection is feasible, safe, and associated with minimal toxicity, according to a pilot study published in the Journal of the National Cancer Institute.1
Patients with HPV-related oropharyngeal cancers typically have good outcomes but experience clinically significant toxicities when treated with standard chemoradiotherapy at a dose…

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